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About the Portal

Overview of the ELITE Portal Platform

The ELITE Portal is a public data repository that stores and shares multi-omic data and tools generated by multiple collaborative research programs focused on exceptional longevity translational research in human cohorts and non-human species.

The data housed in this portal is primarily generated by research projects funded by the National Institute of Aging (NIA). These programs embrace open science principles and require data to be released in a rapid manner, according to the NIH Genomic Data Sharing Policy and NIH Data Management and Sharing Policy.

The ELITE Portal is designed to support transparent evaluation and broad use of resources generated within the NIA's translational research portfolio. All data, methods, and results generated are distributed under FAIR (Findable, Accessible, Interoperable, and Reusable; Wilkinson et al., 2016) principles according to the NIH Genomic Data Sharing Policy.

The ELITE Portal & Synapse

How do the ELITE Portal and Synapse fit together? Let’s break this down:

Sage Bionetworks

Sage Bionetworks is a non-profit organization based out of Seattle, Washington dedicated to promoting and advancing open science, as well as engaging patients in the research process. Sage acts as the Data Coordinating Center (DCC) for several different research consortia, including the National Institute on Aging (NIA) funded exceptional longevity translational research consortium. The scientists, developers, and designers that built this data portal and its underlying infrastructure are all employed by Sage. Learn more about Sage Bionetworks and its initiatives here.

Synapse

In line with advocating for open science, Sage developed a software platform called Synapse. This platform is what allows for collaborative data curation and analysis, computational modelling, and more. It allows users to upload, store, analyze, and track data in a private space, before releasing it to the public-facing ELITE Portal. Think of Synapse as the back-end for all the data to live in.

ELITE Portal

If Synapse is the back-end for data, the ELITE Portal is the front. It’s essentially the user interface (UI) or entry point for you to view data and other shared content. Data gets uploaded into Synapse and is made accessible for you in the portal.

About the EL DMCC

The ELITE Portal is supported by the Data Management and Coordinating Center (DMCC) and a Collaborative research Space for Translational Research on Exceptional Longevity funding opportunity initiated by the National Institutes of Health (NIH) and awarded to Sage Bionetworks. This opportunity supports the expansion and distribution of data and resources generated by the longevity translational projects and helped to further the goals of increasing collaborative research activities and engagement with the broader longevity research community.

The EL DMCC is responsible for:

  • Monitoring user-contributed data to ensure it complies with the terms and conditions for funding

  • Supporting data contributors as needed when it comes to uploading and disseminating data

  • Supporting collaboration among data contribution teams

  • Distributing data to the general research community

  • Providing general support to the following tools:

    • Synapse

    • ELITE Portal

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